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PubMed COVID-19 Clinical Care

2641 - 2650 of 5135 results found

Alkyne as a Latent Warhead to Covalently Target SARS-CoV-2 Main Protease

Date
Friday, August 18, 2023 - 4:00 AM
Description
There is an urgent need for improved therapy to better control the ongoing COVID-19 pandemic. The main protease M^(pro) plays a pivotal role in SARS-CoV-2 replications, thereby representing an attractive target for antiviral development. We seek to

ACE2 receptor: a potential pharmacological target in COVID-19

Date
Thursday, August 17, 2023 - 4:00 AM
Description
Studies have shown that injection of recombinant angiotensin-converting enzyme 2 (ACE2) significantly increased circulatory levels of ACE2 activity, reduced cardiac hypertrophy and fibrosis, and effectively lowered blood pressure. In addition